- Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole.
Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole.
Chemical communications (Cambridge, England) (2008-03-28)
Jun-Long Zhang, Dewain K Garner, Lei Liang, Qian Chen, Yi Lu
PMID18368158
摘要
We demonstrate that incorporation of MnSalen into a protein scaffold enhances the chemoselectivity in sulfoxidation of thioanisole and find that both the polarity and hydrogen bonding of the protein scaffold play an important role in tuning the chemoselectivity.
材料