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Merck
  • A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.

A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.

Chemical communications (Cambridge, England) (2005-12-24)
Daniel Brayton, Faith E Jacobsen, Seth M Cohen, Patrick J Farmer
摘要

A one-pot reaction of maltol with Lawesson's reagent generates dithiomaltol, a thiopyran-4-thione, via an unusual heterocyclic atom exchange (HCAE) reaction; only pyrones with proton or aliphatic substituents undergo the HCAE substitution.

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Sigma-Aldrich
Lawesson 试剂, 97%