- Androstenediol analogs as ER-beta-selective SERMs.
Androstenediol analogs as ER-beta-selective SERMs.
Bioorganic & medicinal chemistry letters (2005-11-29)
Timothy A Blizzard, Candido Gude, Jerry D Morgan, Wanda Chan, Elizabeth T Birzin, Marina Mojena, Consuelo Tudela, Fang Chen, Kristin Knecht, Qin Su, Bryan Kraker, Ralph T Mosley, Mark A Holmes, Nandini Sharma, Paula M D Fitzgerald, Susan P Rohrer, Milton L Hammond
PMID16309907
摘要
A series of 19-substituted androstenediol derivatives was prepared. Some of the novel analogs were surprisingly potent and selective ligands for ER-beta.
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