- Lethal Outcome of Leptospirosis in Southern Russia: Characterization of Leptospira Interrogans Isolated from a Deсeased Teenager.
Lethal Outcome of Leptospirosis in Southern Russia: Characterization of Leptospira Interrogans Isolated from a Deсeased Teenager.
International journal of environmental research and public health (2020-06-18)
Andrei E Samoilov, Nataliya A Stoyanova, Nikolai K Tokarevich, Birgitta Evengard, Elena V Zueva, Yulia A Panferova, Yulia V Ostankova, Elena B Zueva, Diana E Valutite, Evgeniy V Kovalev, Anna R Litovko, Alexey U Goncharov, Alexandr V Semenov, Kamil Khafizov, Vladimir G Dedkov
PMID32545855
摘要
This article describes a lethal case of leptospirosis that occurred in Southern Russia. The Leptospira strain was isolated and characterized using a microscopic agglutination test, MALDI-TOF mass spectrometry, targeted PCR, and high-throughput sequencing. We show that molecular and mass-spectrometry methods can be an alternative to conventional methods of leptospirosis diagnostics and Leptospira study, which require highly qualified staff and can be performed only at specialized laboratories. We also report the first whole genome of L. interrogans isolated in Russia.
材料