Megalin - a facultative marker of obesity-related glomerulopathy in children.

Megalin - a facultative marker of obesity-related glomerulopathy in children.

Journal of biological regulators and homeostatic agents (2019-04-11)

D Ostalska-Nowicka, K Mackowiak-Lewandowicz, B Perek, K Zaorska, J Zachwieja, M Nowicki

摘要

Obesity-related glomerulopathy (ORG) is an increasingly detected syndrome present in children with obesity. Megalin, a constitutive proximal tubule cell protein, when present in urine, can be considered as a biomarker indicating renal injury in these children.