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Merck
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Key Documents

SRP6553

Sigma-Aldrich

CIRBP/冷诱导 RNA 结合蛋白 人

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

别名:

A18HNRNP, CIRP

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥90% (SDS-PAGE)

形狀

lyophilized

分子量

20.5 kDa

包裝

pkg of 1 mg
pkg of 20 μg

雜質

≤1 EU/μg endotoxin (LAL test)

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−70°C

基因資訊

human ... CIRBP(1153)

一般說明

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

外觀

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

重構

Detailed reconstitution instructions are sent along with the product

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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