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生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
分子量
antigen predicted mol wt 420 kDa
物種活性
mouse, rat, human
濃度
1 mg/mL
技術
immunohistochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... BSN(8927)
一般說明
Bassoon presynaptic cytomatrix protein (BSN) is a 420kDa protein which is expressed in the neuronal synapses. The gene encoding it is located on human chromosome 3p21. The gene ID of the protein is 8927.
特異性
Detects ~420 kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected.
免疫原
NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
生化／生理作用
Bassoon presynaptic cytomatrix protein (BSN) acts as a scaffold protein and mediates release of neurotransmitters. It is also a part of trafficking and helps in delivery of proteins across the synapse.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
PBS, pH 7..4, 50% glycerol, 0.09% sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
C Winter et al.
Genomics, 57(3), 389-397 (1999-05-18)
Bassoon is a novel 420-kDa protein recently identified as a component of the cytoskeleton at presynaptic neurotransmitter release sites. Analysis of the rat and mouse sequences revealed a polyglutamine stretch in the C-terminal part of the protein. Since it is
Stefan Hallermann et al.
Neuron, 68(4), 710-723 (2010-11-26)
Sustained rate-coded signals encode many types of sensory modalities. Some sensory synapses possess specialized ribbon structures, which tether vesicles, to enable high-frequency signaling. However, central synapses lack these structures, yet some can maintain signaling over a wide bandwidth. To analyze
Christopher Patzke et al.
Cell, 179(2), 498-513 (2019-10-05)
Neuromodulators bind to pre- and postsynaptic G protein-coupled receptors (GPCRs), are able to quickly change intracellular cyclic AMP (cAMP) and Ca2+ levels, and are thought to play important roles in neuropsychiatric and neurodegenerative diseases. Here, we discovered in human neurons
Nature, 447(7145), 661-678 (2007-06-08)
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the
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