生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 64 kDa
物種活性
mouse, rat, human
濃度
~1 mg/mL
技術
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pSer323)
基因資訊
human ... CDC25B(994)
一般說明
CDC25B (cell division cycle 25B), a short half-life protein belongs to the dual-specificity CDC25 phosphatases family. It is located on human chromosome 20p. The protein is upregulated in late G2 of the cell cycle.
免疫原
The antiserum was produced against synthesized peptide derived from human CDC25B around the phosphorylation site of Ser323.
Immunogen Range: 289-338
Immunogen Range: 289-338
生化／生理作用
The expression of CDC25B (cell division cycle 25B) can be considered as a prognostic marker in the pathogenesis of retinoblastoma. It helps to dephosphorylate CDK1 (cyclin-dependent kinase 1) and ERK1/2 (extracellular signal-regulated kinase 1/2). It controls the cell cycle.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Expression of CDC25A and CDC25B phosphatase proteins in human retinoblastoma and its correlation with clinicopathological parameters
Singh L, et al.
The British Journal of Ophthalmology, 99(4), 457-463 (2015)
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition
Dutertre S, et al.
Journal of Cell Science (2004)
Comparative genomic hybridization analysis of genetic aberrations associated with development of esophageal squamous cell carcinoma in Henan, China
Qin YR, et al.
World Journal of Gastroenterology, 14(12), 1828-1835 (2008)
Targeting cell division cycle 25 homolog B to regulate influenza virus replication
Perwitasari O, et al.
Journal of Virology, 87(24), 13775-13784 (2013)
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