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Merck

C8679

Sigma-Aldrich

芝加哥天蓝 6B

powder

别名:

滂胺天蓝, 直接蓝 1

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About This Item

经验公式(希尔记法):
C34H24N6Na4O16S4
CAS号:
分子量:
992.80
顏色索引編號:
24410
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

形狀

powder

成份

Dye content, ~80%

顏色

blue

溶解度

H2O: 10 mg/mL

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

[Na+].[Na+].[Na+].[Na+].COc1cc(ccc1\N=N\c2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)-c4ccc(\N=N\c5ccc6c(cc(c(N)c6c5O)S([O-])(=O)=O)S([O-])(=O)=O)c(OC)c4

InChI

1S/C34H28N6O16S4.4Na/c1-55-23-11-15(3-7-19(23)37-39-21-9-5-17-25(57(43,44)45)13-27(59(49,50)51)31(35)29(17)33(21)41)16-4-8-20(24(12-16)56-2)38-40-22-10-6-18-26(58(46,47)48)14-28(60(52,53)54)32(36)30(18)34(22)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

InChI 密鑰

BPHHNXJPFPEJOF-GPTZEZBUSA-J

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應用

芝加哥天蓝 6B(Chicago Sky Blue 6B)是荧光和免疫荧光组织化学中背景自发荧光的复染剂。它也被用作玻璃移液管电极的填充物,用于大鼠大脑切片的电生理记录。

生化/生理作用

Chicago Sky Blue 6B 是一种大型有机酸,在结构上与谷氨酸盐相关,是一种强效高效的囊泡谷氨酸盐摄取竞争性抑制剂。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Because both Toll-like receptor-1 (TLR1) and TLR2 are expressed in atherosclerotic plaques, we hypothesized that TLR1 and TLR2 may play different roles in the formation of vulnerable plaques and that combinatorial knockdown of TLR1 and TLR2 genes may enhance the
S Roseth et al.
Journal of neurochemistry, 65(1), 96-103 (1995-07-01)
In this study we have described a series of new and potent inhibitors of the vesicular uptake of glutamate. The two most efficient inhibitors were the dyes Evans blue and Chicago Skye Blue 6B, which are structurally related to glutamate
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Clinical studies have demonstrated that exposure to the inhalational general anesthetic nitrous oxide (N2O) produces antidepressant effects in depressed patients. However, the mechanisms underlying the antidepressant effects of N2O remain largely unknown. Neuronal nitric oxide synthase (nNOS)-mediated nitric oxide (NO)

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