所有图片(1)
About This Item
经验公式（希尔记法）:
C26H21N3O3
CAS号:
分子量:
423.46
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.32
推荐产品
化驗
≥95% (TLC)
形狀
solid
溶解度
methanol and ethanol: soluble
儲存溫度
−20°C
SMILES 字串
Oc1ccc(CC2=NC3=C(Cc4ccccc4)NC(=CN3C2=O)c5ccc(O)cc5)cc1
InChI
1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
InChI 密鑰
YHIPILPTUVMWQT-UHFFFAOYSA-N
一般說明
腔肠素是萤光素分子，可被多种萤光素酶利用，如 海肾属、刺虾属 和绿叶水母中存在的荧光素酶。
應用
天然腔肠素用于：
- 水母发光蛋白测定
- 在 COS-7 细胞中使用水母发光蛋白测量离子霉素或 PMA 诱导的细胞内钙离子浓度
- 在生物发光成像中分析病毒依赖性荧光素酶活性的存在
生化／生理作用
当 Ca 2 + 与复合物结合时，水母发光蛋白复合物的发光基团被氧气氧化并在 465 nm 处发光；用于测量细胞内 Ca 2 + 浓度，灵敏度高，动态范围大。
注意
避免光照
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
New bioluminescent coelenterazine derivatives with various C-6 substitutions
Jiang T, et al.
Organic & Biomolecular Chemistry, 15(33), 7008-7018 (2017)
Darren R Ritsick et al.
Free radical biology & medicine, 43(1), 31-38 (2007-06-15)
The catalytic subunit gp91phox (Nox2) of the NADPH oxidase of mammalian phagocytes is activated by microbes and immune mediators to produce large amounts of reactive oxygen species (ROS) which participate in microbial killing. Homologs of gp91phox, the Nox and Duox
I Gentschev et al.
Cancer gene therapy, 16(4), 320-328 (2008-10-25)
Mammary cancers together with cancers of the skin account for about 60% of the total cancers occurring in dogs. The veterinary options for therapeutic management of canine mammary cancer are limited and prognosis for such patients is poor. In this
Satoshi Inouye et al.
Protein expression and purification, 88(1), 150-156 (2013-01-01)
The cold-induced expression system in Escherichia coli is useful and we have applied this system to prepare the coelenterazine-utilizing luciferases including Renilla luciferase (RLase), a red-shifted variant of Renilla luciferase (RLase-547), the catalytic domain of Oplophorus luciferase (19kOLase) and Gaussia
M Sarah S Bovenberg et al.
Analytical chemistry, 84(2), 1189-1192 (2011-12-14)
Secreted Gaussia luciferase (Gluc) has been shown to be a useful tool for ex vivo monitoring of in vivo biological processes. The Gluc level in the blood was used to detect tumor growth, metastasis and response to therapy, gene transfer
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门