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Merck
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Key Documents

449R-1

Sigma-Aldrich

S100 beta (EP32) Rabbit Monoclonal Primary Antibody

别名:

S100 Calcium Binding Protein B

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP32, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (449R-14)
vial of 0.1 mL concentrate Research Use Only (449R-14-RUO)
vial of 0.5 mL concentrate (449R-15)
vial of 1.0 mL concentrate (449R-16)
vial of 1.0 mL concentrate Research Use Only (449R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (449R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (449R-17)
vial of 7.0 mL pre-dilute ready-to-use (449R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (449R-18-RUO)

製造商／商標名

Cell Marque™

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

同型

IgG

控制

melanoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

一般說明

S100 calcium binding protein B (S100 beta) is a member of the multifunctional S100 family of proteins. S100 beta acts as a stimulator of proliferation and migration and as an inhibitor of apoptosis and differentiation in many cell types including astrocytes, Schwann cells, chondrocytes, adipocytes, certain neuronal populations, melanocytes, Langerhans cells, histiocytes, epithelial, and myoepithelial cells. S100 beta is also expressed in neoplasms derived from these cell types, making it a useful marker for the identification of melanoma and various nervous system tumors. Although ubiquitous, S100 beta has proven to be a sensitive marker for malignant melanoma, including desmoplastic and metastatic variants.

品質


IVD
IVD
IVD
RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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R Donato et al.
Current molecular medicine, 13(1), 24-57 (2012-07-28)
The S100 protein family consists of 24 members functionally distributed into three main subgroups: those that only exert intracellular regulatory effects, those with intracellular and extracellular functions and those which mainly exert extracellular regulatory effects. S100 proteins are only expressed
C deBlacam et al.
British journal of cancer, 105(1), 118-123 (2011-06-10)
Cutaneous melanoma is an aggressive disease. S100beta is an established biomarker of disease progression; however, the mechanism of its regulation in melanoma is undefined. Expression of HOXC11 and SRC-1 was examined by immunohistochemistry and immunofluorescence. Molecular and cellular techniques were
F Sedaghat et al.
Hippokratia, 12(4), 198-204 (2009-01-23)
The members of the S100 protein family are multifunctional proteins with a regulatory role in a variety of cellular processes. They exert their actions usually through calcium binding, although Zn2+ and Cu2+ have also been shown to regulate their biological
Markku Miettinen et al.
The American journal of surgical pathology, 38(3), 410-420 (2014-02-15)
The SALL4 transcription factor is associated with embryonic cell pluripotency and has been shown as a useful immunohistochemical marker for germ cell tumors. However, information of SALL4 distribution in normal human tissues and non-germ cell tumors is limited. In this

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