27102

柠檬酸 一水合物

puriss., meets analytical specification of Ph. Eur., BP, USP, E330, 99.5-100.5% (based on anhydrous substance), grit

• 别名: 2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate
• 线性分子式: HOC(COOH)(CH₂COOH)₂ · H₂O
• CAS号: 5949-29-1
• 分子量: 210.14
• Beilstein: 4018641
• EC號碼: 201-069-1
• MDL號碼: MFCD00149972
• 分類程式碼代碼: 12352100
• PubChem物質ID: 57648219
• NACRES: NA.21

属性

• 等級: puriss.
• 化驗: 99.5-100.5% (based on anhydrous substance)
• 形狀: grit
• 品質: meets analytical specification of Ph. Eur., BP, USP, E330
• 雜質: residual solvents, complies; ≤0.0005% heavy metals (as Pb); 7.5-8.8% water (Karl Fischer)
• 燃燒殘留物: ≤0.05% (as SO₄)
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• 負離子痕跡: chloride (Cl^-): ≤50 mg/kg; oxalate (as oxalic acid): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• 正離子痕跡: As: ≤1 mg/kg; Ca: ≤200 mg/kg; Cu: ≤10 mg/kg; Fe: ≤10 mg/kg; Hg: ≤1 mg/kg; Pb: ≤1 mg/kg; Zn: ≤10 mg/kg
• 適合性: complies for appearance of solution; complies for identity (IR); complies for reaction against H₂SO₄
• SMILES 字串: OC(CC(O)(C(O)=O)CC(O)=O)=O.O
• InChI: 1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
• InChI 密鑰: YASYEJJMZJALEJ-UHFFFAOYSA-N

说明

一般說明

Citric acid monohydrate is an organic acid. Its molar enthalpy of solution in water has been reported to be Δ_solH_m (298.15K, m = 0.0203molkg^-1) = (29061 ± 123)Jmol^-1

應用

Citric acid monohydrate may be used in the diltiazem hydrochloride (drug) and melt extruded Eudragit RS PO (polymer) formulations. It improves the solubility of drug in the polymer matrix. It may be used to prepare citrate buffer for use in the intravital microscopic studies of adhesion and aggregation of platelets.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 345.0 °F - closed cup
• 閃點（°C）: 173.9 °C - closed cup
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves