推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
6G1.1, monoclonal
物種活性
human
技術
immunohistochemistry: suitable
western blot: suitable
同型
IgG2bκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... NGB(58157)
一般說明
Neuroglobin protein encoded by the gene NGB, is involved in oxygen transport in the brain. Neuroglobin is also important for neuroprotection during oxidative stress. Additionally, Neuroglobin has anti-apoptotic activity by reseting the mitochondrial membrane tigger level for cytochrome C release and the commitment to apoptosis. Neuroglobin is localized to the perikaryon, cytoplasm, and mitochondrion. Neuroglobin is predominantly expressed in the brain with strongest expression in the frontal lobe and the subthalamic nucleus and thalamus.
免疫原
GST-tagged recombinant protein corresponding to the N-terminus of human Neuroglobin.
應用
Detect Neuroglobin using this mouse monoclonal antibody, Anti-Neuroglobin Antibody, clone 6G1.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.
品質
Evaluated by Western Blotting in human cortex tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.
標靶描述
~17 kDa observed
外觀
Format: Purified
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
International journal of molecular sciences, 24(6) (2023-03-30)
A promising therapeutic strategy to delay and/or prevent the onset of neurodegenerative diseases (NDs) could be to restore neuroprotective pathways physiologically triggered by neurons against stress injury. Recently, we identified the accumulation of neuroglobin (NGB) in neuronal cells, induced by
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