207008

Calcineurin Substrate

An excellent peptide substrate for calcineurin.

• 别名: Calcineurin Substrate, PP2B Substrate, RII Phosphopeptide, DLDVPIPGRFDRRVpSVAAE
• 经验公式（希尔记法）: C₉₂H₁₅₁N₂₈O₃₂P
• 分子量: 2192.33
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 溶解度: water: 2 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

An excellent peptide substrate for calcineurin (Protein Phosphatase 2B, PP2B, Cat. No. 539568). The sequence is derived from the PKA regulatory subunit type II (RII) and is phosphorylated on the Ser residue. Release of phosphate can be quantified colorimetrically using malachite green method.

An excellent peptide substrate for calcineurin (Protein Phosphatase 2B, PP2B; Cat. No. 539568). The sequence is derived from the PKA regulatory subunit type II (RII) and is phosphorylated on the Ser residue. Release of phosphate can be quantified colorimetrically using the malachite green method.

生化／生理作用

Cell permeable: no

Primary Target
Calcineurin (Protein Phosphatase 2B, PP2B)

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

序列

H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser(PO₃H₂)-Val-Ala-Ala-Glu-OH

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

其他說明

Donella-Deana, A., et al. 1994. Eur. J. Biochem. 219, 109.
Enz, A., et al. 1994. Anal. Biochem. 216, 147.
Harder, K.W., et al. 1994. Biochem. J. 298, 395.
Fruman, D.A., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 3686.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable