推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
4G12, monoclonal
物種活性（以同源性預測）
all
製造商／商標名
Upstate®
技術
immunoprecipitation (IP): suitable
運輸包裝
wet ice
目標翻譯後修改
acetylation (Lys)
特異性
识别含乙酰赖氨酸的蛋白质，包括组蛋白。
免疫原
化学乙酰化抗原的混合物。 克隆4G12。
應用
用抗乙酰赖氨酸抗体（克隆4G12，琼脂糖偶联物，小鼠单克隆抗体）检测乙酰赖氨酸，该抗体已被证明可在IP中起作用。
研究亚类
常规翻译后修饰
组蛋白
常规翻译后修饰
组蛋白
研究类别
信号传导
表观遗传学&核功能
信号传导
表观遗传学&核功能
特點和優勢
形式：凝胶固定
品質
通过免疫沉淀进行了常规评估。
標靶描述
因检测的蛋白质而异。
儲存和穩定性
自发货之日起在4°C下可保存1年。不可冷冻。
其他說明
浓度：请参考批次特异性浓缩物的检验报告。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Yan Liu et al.
Journal of proteome research, 20(5), 2596-2606 (2021-04-02)
Decreased cellular NAD+ levels are causally linked to aging and aging-associated diseases. NAD+ precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD+
A Villagra et al.
Methods in enzymology, 573, 161-181 (2016-07-04)
Histone deacetylase assays were first developed in the 1970s, and subsequently refined in the 1990s with the cloning of HDAC enzymes. Most of these early assays, relying on traditional in vitro chemical methodologies, are still applicable today. More recently, however
Acetylation of general transcription factors by histone acetyltransferases.
Imhof, A, et al.
Current Biology, 7, 689-692 (1997)
N Munshi et al.
Molecular cell, 2(4), 457-467 (1998-11-11)
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Fei Yue et al.
Aging, 7(10), 839-853 (2015-11-06)
Autophagy controls and executes the turnover of abnormally aggregated proteins. MAP1S interacts with the autophagy marker LC3 and positively regulates autophagy flux. HDAC4 associates with the aggregation-prone mutant huntingtin protein (mHTT) that causes Huntington's disease, and colocalizes with it in
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