14-700

NEK11 Protein, active, 10 µg

• UNSPSC代码: 12352202
• eCl@ss: 32160405

属性

• 重组: expressed in baculovirus infected Sf21 cells
• 质量水平: 100
• 描述: protein target NEK11
• 纯化方式: (Ni²⁺/NTA-agarose)
• 技术: activity assay: suitable
• UniProt登记号: Q8NG66
• 基因信息: human ... NEK11(79858)

说明

一般描述

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

质量

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

物理属性

59.3kDa

储存及稳定性

6 months at -70°C from date of shipment

分析说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H317
• 预防措施声明: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危险分类: Skin Sens. 1
• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable