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Merck

880001O

Avanti

Chol-PEG600

Avanti Research - A Croda Brand 880001O

别名:

Cholesterol-(polyethylene glycol-600)

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About This Item

CAS号:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

liquid

包裝

pkg of 1 × 25 mg (880001O-25mg)

製造商/商標名

Avanti Research - A Croda Brand 880001O

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@]12[C@]([C@](CC[C@H](OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

InChI

1S/C29H50O2/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(31-18-17-30)13-15-28(22,4)27(24)14-16-29(25,26)5/h9,20-21,23-27,30H,6-8,10-19H2,1-5H3

InChI 密鑰

NPYXBHZQVNRAOF-UHFFFAOYSA-N

一般說明

Cholesterol-(polyethylene glycol-600) (Chol-PEG600) is a nonionic amphipathic lipid and a cholesterol derivative. It is a water soluble, non-homogeneous compound containing hydrophobic cholesterol and covalently bound hydrophilic PEG.

生化/生理作用

PEG-cholesterol is widely used for cationic DNA transfection studies, and preparation of liposomes for encapsulated drug delivery.

包裝

5 mL Clear Glass Sealed Ampule (880001O-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
PLoS ONE, 9(9) (2014)
Poly (ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells
Ochi, R, et al.
Testing, 9(9) (2014)
Rikuo Ochi et al.
PloS one, 9(9), e107049-e107049 (2014-09-10)
Cholesterol distributes at a high density in the membrane lipid raft and modulates ion channel currents. Poly(ethylene glycol) cholesteryl ether (PEG-cholesterol) is a nonionic amphipathic lipid consisting of lipophilic cholesterol and covalently bound hydrophilic PEG. PEG-cholesterol is used to formulate
CHOBIMALT: a cholesterol-based detergent
Howell S, et al.
Biochemistry, 49(44), 9572-9583 (2010)

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