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Merck

860457P

Avanti

N-C24:1-deoxysphingosine

N-nervonoyl-1-deoxysphingosine (m18:1/24:1), powder

别名:

N-(15Z-tetracosenoyl)-1-deoxysphing-4-enine (m18:1/24:1); N-C24:1-1-deoxyCer; 110996

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About This Item

经验公式(希尔记法):
C42H81NO2
分子量:
632.10
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (860457P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 860457P

脂質類型

sphingolipids
bioactive lipids

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

The sphingoid bases sphingosine is acylated with fatty acids with varying acyl-chain resulting in the synthesis of 1-deoxydihydroceramides (1-deoxyDHCers). These deoxyDHCers are further converted to 1-deoxyceramides (1-deoxysphingosine) and 1-(deoxymethyl)ceramides. They are produced by mammals.

生化/生理作用

The 1-deoxydihydroceramides are hydrophobic and interact with monolayers and giant unilamellar vesicles. They modulate cell membrane and may affect their biological functionality.

包裝

5 mL Amber Glass Screw Cap Vial (860457P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Biophysical properties of novel 1-deoxy-(dihydro) ceramides occurring in mammalian cells
Jimenez-Rojo N, et al.
Biophysical Journal, 107(12), 2850-2859 (2014)
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now

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