803774

Colby trifluoromethylation reagent

• 别名: Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt
• 经验公式（希尔记法）: C₁₂H₁₈F₆N₂O₂
• CAS号: 1400691-55-5
• 分子量: 336.27
• 分類程式碼代碼: 12352101

属性

• 形狀: solid
• SMILES 字串: OC([O-])(C(F)(F)F)C(F)(F)F.C1CCC2=[N+](CC1)CCCN2

说明

一般說明

Colby trifluoromethylation reagent is an amidinate salt of hexafluoroacetone hydrate. This reagent can be prepared from the ethereal solution of hexafluoroacetone trihydrate. It undergoes various trifluoromethylation reactions with electrophiles under different reaction conditions to afford trifluoromethylated products.[1]

應用

Colby trifluoromethylation reagent may be used for the preparation of fluorinated organic compounds.[1]

The Colby Trifluoromethylation Reagent is an air-stable, white solid, which can be used as a source of fluoroform through the release of trifluoroacetate. This reagent can add trifluoromethyl groups in a nucleophlic fashion to carbonyls and sulfides.

其他說明

Amidinate Salt of Hexafluoroacetone Hydrate for the Preparation of Fluorinated Compounds by the Release of Trifluoroacetate

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H318
• 防範說明: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable