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Key Documents

F5132

Sigma-Aldrich

Factor II 来源于人类血浆

lyophilized powder, 5-20 units/mg protein

别名:

Prothrombin

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200

形狀

lyophilized powder

比活性

5-20 units/mg protein

UniProt登錄號

異物活動

factor X <0.01% of base activity
thrombin, none detected

儲存溫度

−20°C

基因資訊

human ... F2(2147)

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生化/生理作用

Plasma phospholipid binding protein; binds to endothelial cells, promotes clotting on the cell surfaces.

單位定義

One unit is the amount contained in one mL of normal human plasma.

重構

When reconstituted with 1 ml of deionized water, solution will contain the indicated activity in 0.5 M NaCl, 0.05 M Tris-HCl, pH 8.0.

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Ayako Tomono et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 110(5), 852-860 (2013-05-08)
A 78-year-old man was admitted for workup for a liver tumor. Both serum AFP and PIVKA-II levels were high (2260ng/ml and 806mAU/ml, respectively). Contrast-enhanced CT scan and MRI using Gd-EOB-DTPA demonstrated a liver tumor in segment 6 resembling the imaging
György Miklós Buzás
Orvosi hetilap, 154(21), 810-819 (2013-05-23)
Tumor markers are gene products which signal the occurrence of tumors in different organs as well as their response to surgery and chemotherapy. The discovery of tumor markers occurred after the demonstration of tumor-specific transplantation antigens in chemically or virally
Yuichiro Yanagida et al.
Surgery, 154(1), 48-57 (2013-05-21)
We tested the hypotheses that an increase in systemic thrombin activity occurs in both disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype and in acute coagulopathy of trauma shock (ACoTS), and that the patients diagnosed as having ACoTS overlap or
Masahiko Tameda et al.
Cancer science, 104(6), 725-731 (2013-03-14)
Serum tumor markers, including α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP), are currently used in the diagnosis of hepatocellular carcinoma (HCC). There is, however, an aberrant increase in serum DCP in patients with obstructive jaundice, vitamin K deficiency or who are
G V Papatheodoridis et al.
Journal of hepatology, 31(4), 747-750 (1999-11-07)
We evaluated the efficacy of recombinant factor VII to correct impaired haemostasis in a patient with liver cirrhosis requiring an invasive procedure. A test intravenous bolus of 80 microg/kg of recombinant factor VII was given to a Jehovah's Witness, with

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