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Merck

YWHAE

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

别名:
14-3-3E, KCIP-1, MDCR, MDS
物种:
UniProtKB ID:
基因ID:
  • Human(7531) Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(22627) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • Rat(29753) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • chicken(417554) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • dog(480645) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • domestic cat(101101425) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • cow(282125) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • sheep(443300) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • domestic guinea pig(100714396) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  • naked mole-rat(101717238) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

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Antibodies

货号
说明
物种反应性
应用
Anti-YWHAE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-14-3-3 epsilon Antibody, clone 4X6E1, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot

Proteins

货号
说明
物种
14-3-3 ε, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
14-3-3 ε, untagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human YWHAE,
物种
human
MISSION® esiRNA, targeting mouse Ywhae,
物种
mouse