UHRF1
ubiquitin-like with PHD and ring finger domains 1
别名:
ICBP90, Np95, RNF106, hNP95, hUHRF1
物种:
Human UHRF1 (29128), Mouse Uhrf1 (18140), Rat Uhrf1 (316129), chicken UHRF1 (420154), Zebrafish uhrf1 (406350), Zebrafish uhrf1 (100538017), naked mole-rat Uhrf1 (101719703), domestic guinea pig Uhrf1 (100719542), sheep UHRF1 (101113067), cow UHRF1 (530411) ...展开
UniProtKB ID:
基因ID:
- Human(29128) Summary: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18140) ubiquitin-like, containing PHD and RING finger domains, 1
- Rat(316129) ubiquitin-like with PHD and ring finger domains 1
- chicken(420154) ubiquitin-like with PHD and ring finger domains 1
- Zebrafish(406350) ubiquitin-like, containing PHD and RING finger domains, 1
- Zebrafish(100538017) ubiquitin-like with PHD and ring finger domains 1
- naked mole-rat(101719703) ubiquitin-like with PHD and ring finger domains 1
- domestic guinea pig(100719542) ubiquitin-like with PHD and ring finger domains 1
- sheep(101113067) ubiquitin-like with PHD and ring finger domains 1
- cow(530411) ubiquitin-like with PHD and ring finger domains 1
- Horse(100062347) ubiquitin-like with PHD and ring finger domains 1
- domestic cat(101083658) ubiquitin-like with PHD and ring finger domains 1
- dog(611463) ubiquitin-like with PHD and ring finger domains 1
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Antibodies
货号
说明
物种反应性
应用
单克隆抗UHRF1 小鼠抗, clone 3A11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-UHRF1 antibody produced in mouse, clone 3B12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-UHRF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry