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Merck

TP53

tumor protein p53

别名:
BCC7, LFS1, P53, TRP53
物种:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...展开
UniProtKB ID:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
基因ID:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • sheep(443421) tumor protein p53
  • cow(281542) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53

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ELISA

货号
说明
物种
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB5702066
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
物种反应性
mouse
应用
CBL404
抗-p53 抗体，aa 211-220，克隆240, clone PAb240, Chemicon®, from mouse,
物种反应性
bovine, chicken, hamster, human, monkey, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
P6874
Anti- p53 抗体，小鼠单克隆, clone DO-1, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
P8999
抗p53抗体，小鼠单克隆 小鼠抗, clone DO-7, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB56000290
Anti-p53 Rabbit Monoclonal Antibody, clone RM387, affinity purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
western blot

Cell Lines

货号
说明
物种
CLLS1049
MCF10A CELLS TP53 (-/-), ,
物种
human
CLLS1127
DLD1 Cells TP53 -/-, ,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
PZ0115
CP-31398 二盐酸盐 水合物, ≥98% (HPLC),
物种
mouse, rat, human

Proteins

货号
说明
物种
14-865
p53-GST (recombinant protein), ,
物种
P6249
p53 人, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
物种
human
P6374
p53 人, recombinant, expressed in baculovirus infected Sf21 cells,
物种
human
SRP2108
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物种
human
SRP2107
p53 (1-81), wild type, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EHU123221
MISSION® esiRNA, targeting human TP53,
物种
human