TNNI1
troponin I type 1 (skeletal, slow)
别名:
SSTNI, TNN1
物种:
Human TNNI1 (7135), Mouse Tnni1 (21952), Rat Tnni1 (29388), chicken TNNI1 (421161), cow TNNI1 (100301375), dog TNNI1 (100685160), Goat TNNI1 (100860774), domestic guinea pig Tnni1 (100733717), domestic cat TNNI1 (101096197), naked mole-rat Tnni1 (101720739)
UniProtKB ID:
基因ID:
- Human(7135) Summary: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
- Mouse(21952) troponin I, skeletal, slow 1
- Rat(29388) troponin I type 1 (skeletal, slow)
- chicken(421161) troponin I type 1 (skeletal, slow)
- cow(100301375) troponin I type 1 (skeletal, slow)
- dog(100685160) troponin I type 1 (skeletal, slow)
- Goat(100860774) troponin I type 1 (skeletal, slow)
- domestic guinea pig(100733717) troponin I type 1 (skeletal, slow)
- domestic cat(101096197) troponin I type 1 (skeletal, slow)
- naked mole-rat(101720739) troponin I type 1 (skeletal, slow)
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Antibodies
货号
说明
物种反应性
应用
Anti-Cardiac Troponin I Antibody, clone 1F23, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-TNNI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-TNNI1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-TNNI1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-Troponin I1/TnI1 Antibody, clone 5K1U2, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Proteins
货号
说明
物种
Troponin1, His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human