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Merck

THRB

thyroid hormone receptor, beta

别名:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
物种:
UniProtKB ID:
基因ID:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

货号
说明
物种
3,3′,5-三碘-L-甲状腺原氨酸(T3) 溶液, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
L-甲状腺素(T4) 溶液, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
L-甲状腺素, United States Pharmacopeia (USP) Reference Standard,
物种
human
左旋甲状腺素钠, United States Pharmacopeia (USP) Reference Standard,
物种
human
3,3′,5-三碘代-L-甲状腺原氨酸, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
3,3′,5-三碘-L-甲状腺氨酸 钠盐, powder, BioReagent, suitable for cell culture,
物种
rat, human
3,3′,5-三碘代-L-甲状腺原氨酸, ≥95% (HPLC), powder,
物种
rat, human
3,3′,5-三碘-L-甲状腺氨酸 钠盐, γ-irradiated, powder, suitable for, suitable for cell culture,
物种
rat, human
替拉曲可, ≥90%,
物种
rat, human
L-甲状腺素, ≥98% (HPLC),
物种
human, mouse, rat

Antibodies

货号
说明
物种反应性
应用
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
3,3′,5-三碘-L-甲状腺氨酸 钠盐, powder, BioReagent, suitable for cell culture,
物种
rat, human
3,3′,5-三碘代-L-甲状腺原氨酸, ≥95% (HPLC), powder,
物种
rat, human
3,3′,5-三碘-L-甲状腺氨酸 钠盐, γ-irradiated, powder, suitable for, suitable for cell culture,
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human THRB,
物种
human