RNF8
ring finger protein 8, E3 ubiquitin protein ligase
别名:
hRNF8
物种:
Human RNF8 (9025), Mouse Rnf8 (58230), Rat Rnf8 (361815), naked mole-rat Rnf8 (101703952), domestic guinea pig Rnf8 (100725403), sheep RNF8 (101103680), chicken RNF8 (421435), domestic cat RNF8 (101082654), dog RNF8 (481775), Zebrafish rnf8 (404050)
UniProtKB ID:
基因ID:
- Human(9025) Summary: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- Mouse(58230) ring finger protein 8
- Rat(361815) ring finger protein 8, E3 ubiquitin protein ligase
- naked mole-rat(101703952) ring finger protein 8, E3 ubiquitin protein ligase
- domestic guinea pig(100725403) ring finger protein 8, E3 ubiquitin protein ligase
- sheep(101103680) ring finger protein 8, E3 ubiquitin protein ligase
- chicken(421435) ring finger protein 8, E3 ubiquitin protein ligase
- domestic cat(101082654) ring finger protein 8, E3 ubiquitin protein ligase
- dog(481775) ring finger protein 8, E3 ubiquitin protein ligase
- Zebrafish(404050) ring finger protein 8, E3 ubiquitin protein ligase
- cow(515933) ring finger protein 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
esiRNA
货号
说明
物种