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Merck

PCDHA2

protocadherin alpha 2

别名:
PCDH-ALPHA2
物种:
UniProtKB ID:
基因ID:
  • Human(56146) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  • Mouse(353234) protocadherin alpha 2
  • Rat(393086) protocadherin alpha 2
  • cow(100847133) protocadherin alpha 2
  • dog(487164) protocadherin alpha 2
  • domestic guinea pig(100713044) protocadherin alpha 2
  • sheep(101122274) protocadherin alpha 2
  • chicken(497212) protocadherin alpha 2

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Antibodies

货号
说明
物种反应性
应用
Anti-PCDHA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-PCDHA2 antibody produced in mouse, clone 2G12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PCDHA2,
物种
human