P4HB
prolyl 4-hydroxylase, beta polypeptide
别名:
DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB
物种:
Human P4HB (5034), Mouse P4hb (18453), Rat P4hb (25506), sheep P4HB (100135700), Zebrafish p4hb (406673), sheep P4HB (101115218), chicken P4HB (374091), naked mole-rat P4hb (101712215), cow P4HB (281373), dog P4HB (483369) ...展开
UniProtKB ID:
基因ID:
- Human(5034) Summary: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
- Mouse(18453) prolyl 4-hydroxylase, beta polypeptide
- Rat(25506) prolyl 4-hydroxylase, beta polypeptide
- sheep(100135700) prolyl 4-hydroxylase, beta polypeptide
- Zebrafish(406673) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
- sheep(101115218) prolyl 4-hydroxylase, beta polypeptide
- chicken(374091) prolyl 4-hydroxylase, beta polypeptide
- naked mole-rat(101712215) prolyl 4-hydroxylase, beta polypeptide
- cow(281373) prolyl 4-hydroxylase, beta polypeptide
- dog(483369) prolyl 4-hydroxylase, beta polypeptide
- domestic guinea pig(100733944) prolyl 4-hydroxylase, beta polypeptide
- Domestic Rabbit(100328595) prolyl 4-hydroxylase, beta polypeptide
- domestic cat(101099917) prolyl 4-hydroxylase, beta polypeptide
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Antibodies
货号
说明
物种反应性
应用
Anti-P4HB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PDI Antibody, clone 1M19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, human, monkey, mouse, porcine, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-P4HB (AB2) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human, mouse, pig, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-P4HB antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
货号
说明
物种