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Merck

P2RX1

purinergic receptor P2X, ligand-gated ion channel, 1

别名:
P2X1
物种:
UniProtKB ID:
基因ID:
  • Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
  • Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
  • Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
  • Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
  • Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
  • cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
  • sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1
  • Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
  • chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
  • dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
  • naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1

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Small Molecule - Agonist

货号
说明
物种
Α, β-亚甲基腺苷 5′-三磷酸盐 锂盐, ≥93% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
活性蓝 4, Dye content 35 %,
物种
rat
NF 023 hydrate, ≥98% (HPLC), solid,
物种
human
磷酸吡哆醛-6-偶氮(苯-2,4-二磺酸) 四钠盐 水合物, solid, ≥98% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-P2RX1 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
dog, horse, human
应用
immunohistochemistry
western blot
Anti-P2RX1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-P2Rx1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-P2X1 Purinergic Receptor antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
Suramin 钠盐, ≥98% (TLC),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human P2RX1,
物种
human
MISSION® esiRNA, targeting mouse P2rx1,
物种
mouse