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Merck

NTRK1

neurotrophic tyrosine kinase, receptor, type 1

别名:
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
物种:
Human NTRK1 (4914), Mouse Ntrk1 (18211), Rat Ntrk1 (59109), chicken NTRK1 (396337), domestic cat NTRK1 (101081603), domestic guinea pig Ntrk1 (100725325), naked mole-rat Ntrk1 (101724441), cow NTRK1 (353111), sheep NTRK1 (101109763), Domestic Rabbit NTRK1 (100354292) ...展开
UniProtKB ID:
P04629, B2R6T5, B7ZM34, P08119, Q15655, Q15656, Q5D056, Q5VZS2
基因ID:
  • Human(4914) Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
  • Mouse(18211) neurotrophic tyrosine kinase, receptor, type 1
  • Rat(59109) neurotrophic tyrosine kinase, receptor, type 1
  • chicken(396337) neurotrophic tyrosine kinase, receptor, type 1
  • domestic cat(101081603) neurotrophic tyrosine kinase, receptor, type 1
  • domestic guinea pig(100725325) neurotrophic tyrosine kinase, receptor, type 1
  • naked mole-rat(101724441) neurotrophic tyrosine kinase, receptor, type 1
  • cow(353111) neurotrophic tyrosine kinase, receptor, type 1
  • sheep(101109763) neurotrophic tyrosine kinase, receptor, type 1
  • Domestic Rabbit(100354292) neurotrophic tyrosine kinase, receptor, type 1
  • Horse(100064594) neurotrophic tyrosine kinase, receptor, type 1
  • dog(490404) neurotrophic tyrosine kinase, receptor, type 1
  • Zebrafish(30546) neurotrophic tyrosine kinase, receptor, type 1

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ELISA

货号
说明
物种
RAB1757
人TrkA ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4502031
Anti-TRK A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
HPA035799
Anti-NTRK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB1305087
ANTI-PHOSPHO-TRKA(Y791) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
SAB1305365
ANTI-TRKA (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
flow cytometry
western blot
SAB4300254
Anti-phospho-NTRK1 (pSer791) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence

Small Molecule - Inhibitor

货号
说明
物种
K1639
K-252a, from Nonomuraea longicatena, ≥98% (HPLC),
物种
rat, human
K2015
K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%,
物种
rat, human
T2067
Tyrphostin AG 879, 99% (HPLC),
物种
human

Proteins

货号
说明
物种
T4202
TRKA (440-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EHU081661
MISSION® esiRNA, targeting human NTRK1,
物种
human
EMU063891
MISSION® esiRNA, targeting mouse Ntrk1,
物种
mouse