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Merck

KCNA3

potassium voltage-gated channel, shaker-related subfamily, member 3

别名:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
物种:
UniProtKB ID:
基因ID:
  • Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
  • cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
  • dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3
  • chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
  • naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
  • sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3

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Antibodies

货号
说明
物种反应性
应用
Anti-KV1.3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-KCNA3 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-Potassium Channel Kv1.3 (extracellular)−FITC antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human, mouse, rat
应用
flow cytometry
western blot

Small Molecule - Blocker

货号
说明
物种
Charybdotoxin, ≥90% (HPLC),
物种
mouse, rat, human
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物种
human
盐酸胍 盐酸盐, ≥98%,
物种
human
盐酸胍 盐酸盐, ≥99% (titration), organic base and chaeotropic agent,
物种
human
盐酸胍 盐酸盐, ,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human KCNA3,
物种
human