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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

别名:
IMPD, IMPD1, LCA11, RP10, sWSS2608
物种:
UniProtKB ID:
基因ID:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-IMPDH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
利巴韦林, United States Pharmacopeia (USP) Reference Standard,
物种
human
利巴韦林杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human
利巴韦林, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
利巴韦林, European Pharmacopoeia (EP) Reference Standard,
物种
human
利巴韦林, British Pharmacopoeia (BP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human IMPDH1,
物种
human
MISSION® esiRNA, targeting mouse Impdh1,
物种
mouse