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Merck

HTR5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

别名:
5-HT5A
物种:
Human HTR5A (3361), Mouse Htr5a (15563), Rat Htr5a (25689), cow HTR5A (541200), Horse HTR5A (100063709), domestic cat HTR5A (101084611), Zebrafish htr5a (100038775), dog HTR5A (482814), sheep HTR5A (101116905), naked mole-rat Htr5a (101723065) ...展开
UniProtKB ID:
P47898, Q2M2D2
基因ID:
  • Human(3361) Summary: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
  • Mouse(15563) 5-hydroxytryptamine (serotonin) receptor 5A
  • Rat(25689) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • cow(541200) 5-hydroxytryptamine (serotonin) receptor 5A
  • Horse(100063709) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic cat(101084611) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • Zebrafish(100038775) 5-hydroxytryptamine (serotonin) receptor 5A
  • dog(482814) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • sheep(101116905) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • naked mole-rat(101723065) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic guinea pig(100379278) 5-hydroxytryptamine (serotonin) receptor 5A
  • chicken(428409) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

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Small Molecule - Agonist

货号
说明
物种
C117
5-羧酰胺色胺 马来酸盐, powder, ≥98% (HPLC),
物种
human, rat
Q1004
喹哌嗪 马来酸盐, ,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
D9190
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
C117
5-羧酰胺色胺 马来酸盐, powder, ≥98% (HPLC),
物种
human, rat
A2729
氨磺必利, ≥98% (HPLC),
物种
human
BP1143
系统适用性试验用氨磺必利, British Pharmacopoeia (BP) Reference Standard,
物种
human
A0590000
氨磺必利, European Pharmacopoeia (EP) Reference Standard,
物种
human
Y0001534
氨磺必利, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4501483
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
SAB2900156
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
SAB2900036
Anti-HTR5A (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
SAB2900037
Anti-HTR5A (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, dog, guinea pig, horse, human, monkey, mouse, rat
应用
ELISA
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
Z101
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
F132
氟西汀 盐酸盐, solid,
物种
human
R0875
利血平, ,
物种
human
S6319
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
H9772
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
EHU104651
MISSION® esiRNA, targeting human HTR5A,
物种
human