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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

别名:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
物种:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...展开
UniProtKB ID:
P28222, Q4VAY7
基因ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

货号
说明
物种
S1198
Sumatriptan succinate, ≥98% (HPLC), solid,
物种
human
SML0248
佐米曲普坦, ≥98% (HPLC),
物种
human
1642201
Sumatriptan succinate, United States Pharmacopeia (USP) Reference Standard,
物种
human
1457469
Naratriptan hydrochloride, United States Pharmacopeia (USP) Reference Standard,
物种
human
1286413
Frovatriptan succinate, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
D9190
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
物种
human
M149
甲硫替平 甲磺酸盐, ≥98% (HPLC), solid,
物种
human
T6154
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
P8688
(S)-(-)-普奈洛尔 盐酸盐, ≥98% (TLC), powder,
物种
human
M137
二甲麦角新碱 马来酸盐, solid,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
SAB4501471
抗-HTR1B 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
western blot
SAB2500924
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
T6154
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
P8688
(S)-(-)-普奈洛尔 盐酸盐, ≥98% (TLC), powder,
物种
human
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
Z101
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
T6154
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
F132
氟西汀 盐酸盐, solid,
物种
human
S6319
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
H9772
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
物种
mouse