HR
hair growth associated
别名:
ALUNC, AU, HSA277165, MUHH, MUHH1
物种:
Human HR (55806), Mouse Hr (15460), Rat Hr (60563), Horse HR (100053727), domestic cat HR (101090097), dog HR (486130), Domestic Rabbit HR (100357019), sheep HR (443241), cow HR (785815), naked mole-rat Hr (101710794)
UniProtKB ID:
基因ID:
- Human(55806) Summary: This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR, cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
- Mouse(15460) hairless
- Rat(60563) hair growth associated
- Horse(100053727) hairless homolog (mouse)
- domestic cat(101090097) hairless homolog (mouse)
- dog(486130) hairless homolog (mouse)
- Domestic Rabbit(100357019) hairless homolog (mouse)
- sheep(443241) hairless homolog (mouse)
- cow(785815) hairless homolog (mouse)
- naked mole-rat(101710794) hair growth associated
- domestic guinea pig(100726903) hair growth associated
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Antibodies
货号
说明
物种反应性
应用
Anti-HAIR antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry