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Merck

HEXB

hexosaminidase B (beta polypeptide)

别名:
ENC-1AS
物种:
UniProtKB ID:
基因ID:
  • Human(3074) Summary: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008]
  • Mouse(15212) hexosaminidase B
  • Rat(294673) hexosaminidase B
  • naked mole-rat(101713145) hexosaminidase B (beta polypeptide)
  • chicken(427204) hexosaminidase B (beta polypeptide)
  • dog(478100) hexosaminidase B (beta polypeptide)
  • domestic cat(493928) hexosaminidase B (beta polypeptide)
  • sheep(101111906) hexosaminidase B (beta polypeptide)
  • cow(618571) hexosaminidase B (beta polypeptide)
  • Domestic Rabbit(100009508) hexosaminidase B (beta polypeptide)
  • domestic guinea pig(100731613) hexosaminidase B (beta polypeptide)

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Antibodies

货号
说明
物种反应性
应用
Anti-HEXB antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-HEXB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-HEXB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Hexb,
物种
mouse
MISSION® esiRNA, targeting human HEXB,
物种
human