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Merck

GUCA2B

guanylate cyclase activator 2B (uroguanylin)

别名:
GCAP-II, UGN
物种:
UniProtKB ID:
基因ID:
  • Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
  • Mouse(14916) guanylate cyclase activator 2b (retina)
  • Rat(64055) guanylate cyclase activator 2B
  • dog(100684829) guanylate cyclase activator 2B (uroguanylin)
  • naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
  • domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
  • domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
  • Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
  • cow(515664) guanylate cyclase activator 2B (uroguanylin)

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Small Molecule - Antagonist

货号
说明
物种
犬尿喹啉酸, ≥98%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
ANTI-GUCA2B (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot

Proteins

货号
说明
物种
Uroguanylin, ≥90% (HPLC),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GUCA2B,
物种
human