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Merck

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

别名:
CAE2, ECA2, GEFSP3
物种:
Human GABRG2 (2566), Mouse Gabrg2 (14406), Rat Gabrg2 (29709), Horse GABRG2 (100059571), sheep GABRG2 (101118526), Zebrafish gabrg2 (553402), chicken GABRG2 (396289), dog GABRG2 (489141), domestic cat GABRG2 (100286791), cow GABRG2 (282240) ...展开
UniProtKB ID:
P18507, F5HB82, Q6GRL6, Q6PCC3, Q9UDB3, Q9UN15
基因ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

货号
说明
物种
M-039
眠尔通标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
Z-017
唑吡坦标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Z-004
扎来普隆标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
1724350
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
物种
human
M-908
咪达唑仑标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
D-907
地西泮标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Antagonist

货号
说明
物种
E5126
还原胆烷醇酮, ,
物种
human, rat
1273808
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
G7795
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
D126608
丙泊酚, 97%,
物种
human
F6300
Flumazenil, >99% (HPLC), solid,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
SAB2501406
Anti-GABRG2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human, mouse, rat
应用
ELISA
western blot
G0545
Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
bovine, human, mouse, rat
应用
western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
E5126
还原胆烷醇酮, ,
物种
human, rat
G7795
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
P8887
5α-Pregnan-3α-ol-20-one, solid,
物种
human, mouse, rat

esiRNA

货号
说明
物种
EHU083141
MISSION® esiRNA, targeting human GABRG2,
物种
human