FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
别名:
CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
物种:
Human FCGR3A (2214), Rat Fcgr3a (304966), dog FCGR3A (478984), sheep FCGR3A (100192433), cow FCGR3A (281766)
UniProtKB ID:
基因ID:
- Human(2214) Summary: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(304966) Fc fragment of IgG, low affinity IIIa, receptor
- dog(478984) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- sheep(100192433) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- cow(281766) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
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Antibodies
货号
说明
物种反应性
应用
Anti-FCGR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-CD16 antibody produced in mouse, clone MEM-154, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
Anti-CD16A antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP189, affinity isolated antibody,
物种反应性
human
应用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CD16a Antibody, clone 1E6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-CD16-FITC antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, nonhuman primates
应用
FUNC
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
esiRNA
货号
说明
物种