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Merck

CSF1R

colony stimulating factor 1 receptor

别名:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
物种:
Human CSF1R (1436), Mouse Csf1r (12978), Rat Csf1r (307403), domestic guinea pig Csf1r (100726053), naked mole-rat Csf1r (101719513), sheep CSF1R (101109969), cow CSF1R (509418), domestic cat CSF1R (493706), Horse CSF1R (100060422), dog CSF1R (489188)
UniProtKB ID:
P07333, D3DQG2, Q6LDW5, Q6LDY4, Q86VW7
基因ID:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

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ELISA

货号
说明
物种
RAB0978
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
HPA012323
抗CSF1R 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
SAB2501384
Anti-CSF1R antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot
SAB4500500
Anti-CSFR antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
SAB5500088
Anti-CSF-1R antibody, Rabbit monoclonal, clone SP211, recombinant, expressed in proprietary host, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
SAB4500499
Anti-CSFR antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
CDS023580
帕唑帕尼, ,
物种
human

Proteins

货号
说明
物种
F8180
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU174381
MISSION® esiRNA, targeting mouse Csf1r,
物种
mouse
EHU052661
MISSION® esiRNA, targeting human CSF1R,
物种
human