CASP3
caspase 3, apoptosis-related cysteine peptidase
别名:
CPP32, CPP32B, SCA-1
物种:
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), dog CASP3 (403567), chicken CASP3 (395476), naked mole-rat Casp3 (101712867), domestic guinea pig Casp3 (100718309), cow CASP3 (408016), Domestic Rabbit CASP3 (100008840), sheep CASP3 (443031) ...展开
UniProtKB ID:
基因ID:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
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Antibodies
货号
说明
物种反应性
应用
抗胱天蛋白酶3抗体，活性（裂解）形式, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
抗-半胱天冬酶-3抗体，克隆3J16，ZooMAb®兔单克隆抗体, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, human, mouse, rat
应用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-Caspase 3 antibody produced in mouse, clone 84803.111, purified immunoglobulin, lyophilized powder,
物种反应性
human
应用
western blot
抗-半胱天冬酶3 兔抗, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
microarray
western blot
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
半胱天冬酶 3 人, ≥85% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
物种
human
esiRNA
货号
说明
物种