ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
别名:
A4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2
物种:
Human ATP6V0A4 (50617), Mouse Atp6v0a4 (140494), Rat Atp6v0a4 (296981), sheep ATP6V0A4 (101104057), cow ATP6V0A4 (518974), dog ATP6V0A4 (482779), domestic cat ATP6V0A4 (101089593), domestic guinea pig Atp6v0a4 (100735854), Horse ATP6V0A4 (100064797), Domestic Rabbit ATP6V0A4 (100347541) ...展开
UniProtKB ID:
基因ID:
- Human(50617) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq, Jul 2008]
- Mouse(140494) ATPase, H+ transporting, lysosomal V0 subunit A4
- Rat(296981) ATPase, H+ transporting, lysosomal V0 subunit A4
- sheep(101104057) ATPase, H+ transporting, lysosomal V0 subunit a4
- cow(518974) ATPase, H+ transporting, lysosomal V0 subunit a4
- dog(482779) ATPase, H+ transporting, lysosomal V0 subunit a4
- domestic cat(101089593) ATPase, H+ transporting, lysosomal V0 subunit a4
- domestic guinea pig(100735854) ATPase, H+ transporting, lysosomal V0 subunit a4
- Horse(100064797) ATPase, H+ transporting, lysosomal V0 subunit a4
- Domestic Rabbit(100347541) ATPase, H+ transporting, lysosomal V0 subunit a4
- chicken(418104) ATPase, H+ transporting, lysosomal V0 subunit a4
- naked mole-rat(101719254) ATPase, H+ transporting, lysosomal V0 subunit a4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-ATP6V0A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-ATP6V0A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry