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Merck

ASCC1

activating signal cointegrator 1 complex subunit 1

别名:
ASC1p50, p50
物种:
UniProtKB ID:
基因ID:
  • Human(51008) Summary: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(69090) activating signal cointegrator 1 complex subunit 1
  • Rat(294512) activating signal cointegrator 1 complex subunit 1
  • Zebrafish(550273) activating signal cointegrator 1 complex subunit 1
  • chicken(423709) activating signal cointegrator 1 complex subunit 1
  • cow(534915) activating signal cointegrator 1 complex subunit 1
  • naked mole-rat(101726495) activating signal cointegrator 1 complex subunit 1
  • domestic cat(101081081) activating signal cointegrator 1 complex subunit 1
  • dog(608331) activating signal cointegrator 1 complex subunit 1
  • sheep(101113387) activating signal cointegrator 1 complex subunit 1
  • Goat(100861081) activating signal cointegrator 1 complex subunit 1

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Antibodies

货号
说明
物种反应性
应用
Anti-ASCC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-ASCC1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ascc1,
物种
mouse
MISSION® esiRNA, targeting human ASCC1,
物种
human