ACTN1
actinin, alpha 1
别名:
BDPLT15
物种:
Human ACTN1 (87), Mouse Actn1 (109711), Rat Actn1 (81634), Domestic Rabbit ACTN1 (100341378), Zebrafish actn1 (560400), naked mole-rat Actn1 (101711839), domestic guinea pig Actn1 (100721342), cow ACTN1 (524770), chicken ACTN1 (373918), domestic cat ACTN1 (101097986) ...展开
UniProtKB ID:
基因ID:
- Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109711) actinin, alpha 1
- Rat(81634) actinin, alpha 1
- Domestic Rabbit(100341378) actinin, alpha 1
- Zebrafish(560400) actinin, alpha 1
- naked mole-rat(101711839) actinin, alpha 1
- domestic guinea pig(100721342) actinin, alpha 1
- cow(524770) actinin, alpha 1
- chicken(373918) actinin, alpha 1
- domestic cat(101097986) actinin, alpha 1
- dog(480369) actinin, alpha 1
- sheep(101122194) actinin, alpha 1
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Antibodies
货号
说明
物种反应性
应用
Anti-α Actinin antibody, Mouse monoclonal, clone BM-75.2, purified from hybridoma cell culture,
物种反应性
human
应用
immunofluorescence
western blot
western blot
抗-α-Actinin抗体，克隆AT6/172, clone AT6/172, Upstate®, from mouse,
物种反应性
human, mouse, rabbit
应用
immunocytochemistry
western blot
western blot
Anti-ACTN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-α Actinin Antibody, clone AT6/172 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-α-Actinin-1 Antibody, clone 2C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
货号
说明
物种
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
物种
mouse, chicken, rat, human