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Merck

A Convenient Reagent for Aldehyde to Alkyne Homologation.

Tetrahedron letters (2009-12-01)
Douglass F Taber, Sha Bai, Peng-Fei Guo
ABSTRACT

An convenient reagent for the one-carbon homologation of an aldehyde to the corresponding alkyne is reported. This reagent allows this conversion to conveniently be carried out on a large scale under ambient conditions.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Diethyl (2-oxo-2-phenylethyl)phosphonate, 97%