Skip to Content

Plasma beta-phenylethylamine in Parkinson's disease.

Plasma beta-phenylethylamine in Parkinson's disease.

The Kurume medical journal (2001-02-24)

Y Miura

ABSTRACT

Plasma beta-phenylethylamine (PEA) levels were determined in 27 patients with Parkinson's disease (PD) in order to evaluate its relation with the severity or clinical course of PD. The plasma PEA concentrations in PD patients were significantly lower (mean +/- SD, 862 +/- 554 pg/ml) than those in the control group (1765 +/- 790 pg/ml) (p < 0.0001). The concentrations of PEA in plasma did not correlate with Hoen and Yahr stage. However, in serial measurements of the PEA of 5 patients in the progressive group of the clinical course of PD, the plasma PEA levels revealed a downward trend after one or two years. On the other hand, in 3 patients of non-progressive group, the plasma PEA remained at the same level. This study suggests that plasma PEA level might reflect nigrostriatal degeneration in patients with PD.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Zinc, shot, 5 mm, 99.999% trace metals basis

Sigma-Aldrich

Zinc, foil, thickness 0.25 mm, 99.999% trace metals basis

Sigma-Aldrich

Strontium, dendritic pieces, purified by distillation, 99.9% trace metals basis

Sigma-Aldrich

Titanium, wire, diam. 0.25 mm, 99.7% trace metals basis

Sigma-Aldrich

Cobalt, rod, diam. 5.0 mm, 99.95% trace metals basis

Sigma-Aldrich

Molybdenum, powder, 1-5 μm, ≥99.9% trace metals basis

Sigma-Aldrich

Cobalt, foil, thickness 1.0 mm, 99.95% trace metals basis

Sigma-Aldrich

Zirconium, foil, thickness 0.1 mm, 99.98% trace metals basis

Sigma-Aldrich

Titanium, 5-10 mm, ≥99.99% trace metals basis (purity exclusive of Na and K content)

Sigma-Aldrich

Cobalt, powder, <150 μm, ≥99.9% trace metals basis

Sigma-Aldrich

Cobalt, wire, diam. 1.0 mm, 99.995% trace metals basis

Sigma-Aldrich

Tin, powder, <150 μm, 99.5% trace metals basis

Sigma-Aldrich

Cobalt, powder, 2 μm particle size, 99.8% trace metals basis

Sigma-Aldrich

Magnesium, grit, ≥99.0% (KT)

Sigma-Aldrich

Copper, turnings, purum p.a., ≥99.0%

Sigma-Aldrich

L-Cystine, ≥99.7% (TLC)

Sigma-Aldrich

Aluminum, powder, ≥91% (complexometric)

Sigma-Aldrich

Copper, foil, thickness 1.0 mm, 99.999% trace metals basis

Sigma-Aldrich

Magnesium, 20-230 mesh, reagent grade, 98%

Sigma-Aldrich

Chromium, chips, 99.995% trace metals basis

Sigma-Aldrich

Magnesium, turnings, 5-25 mm, 99.95% trace metals basis

Sigma-Aldrich

Vanadium, foil, thickness 0.127 mm, 99.7% trace metals basis

Sigma-Aldrich

Titanium, foil, thickness 0.127 mm, 99.7% trace metals basis

Sigma-Aldrich

Copper, powder, <75 μm, 99%

Sigma-Aldrich

Titanium, foil, thickness 0.025 mm, 99.98% trace metals basis

Sigma-Aldrich

Zinc, dust, <10 μm, ≥98%

Sigma-Aldrich

Cobalt, granular, 99.99% trace metals basis

Sigma-Aldrich

Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis

Sigma-Aldrich

Strontium, dendritic pieces, purified by distillation, 99.99% trace metals basis

Sigma-Aldrich

Manganese, powder, ≥99.9% trace metals basis