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AMP-activated protein kinase, super metabolic regulator.

Biochemical Society transactions (2003-01-28)
B E Kemp, D Stapleton, D J Campbell, Z-P Chen, S Murthy, M Walter, A Gupta, J J Adams, F Katsis, B van Denderen, I G Jennings, T Iseli, B J Michell, L A Witters
ABSTRACT

The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.