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Bobbitt Group – Professor Product Portal
Dr. James Bobbitt has been developing the chemistry of oxoammonium salts, such as Bobbitt's Salt (Product 745537), for 30 years. He discovered the oxoaommonium chemistry by accident in 1985 and found that it had been started by a fine Russian
Shafi Khan
Research scientist Shafi Ullah Khan is using AI to improve breast cancer treatment – he told us how his having ‘crazy ideas’ supported motivates him to keep going.
Samantha Green
Samantha Green tells us about her work on dual catalysis at the Scripps Research Institute and the need to pursue crazy ideas.
Barbara Guinn
Dr. Barbara Guinn is looking to find ways for a faster diagnosis of endometriosis. She tells us about the women who inspire her to pursue her work and why it’s so important.
Maria Isabel Amorin
María Isabel Amorín is a MSc student at the University of Edinburgh and the creator of CrustaTec, a project that aims to solve two of Guatemala’s biggest environmental problems in one go.
Frederick West
Prof Frederick West tells us how a discussion with a Ph.D. student informed his current work on antiviral drugs to tackle the COVID-19 pandemic.
Kevin Lam
Dr. Kevin Lam, Associate Professor at the University of Greenwich, tells us about his journey within electrosynthesis: from its beginnings as a niche discipline to the burgeoning field it is today.
Ramis Arbi
Working in the field of photovoltaics, Ph.D. candidate Ramis Arbi tells us about the challenges of breaking free from fossil fuels.
Molander Group – Professor Product Portal
The central theme of the Molander group's research is the development of new synthetic methods and their application to the synthesis of organic molecules.
Morken Group – Professor Product Portal
Chiral organoboronic esters are well known as versatile intermediates for chemical synthesis. Not only are these compounds stable under a variety of reaction conditions, they are generally non-toxic and can be transformed with minimal generation of hazardous waste.
Johnson Group – Professor Product Portal
The Johnson group has developed a family of reagents that are useful for the modular preparation of highly substituted glycolic acid derivatives. Silyl glyoxylates are potent electrophiles by virtue of being α-dicarbonyls, and react with a variety of nucleophiles.
Kürti Group – Professor Product Portal
Amines and their derivatives are ubiquitous substances since they make up the overwhelming majority of drug molecules, agrochemicals as well as many compounds that are produced by plants and living organisms (i.e., natural products).
Kwon Group – Professor Product Portal
The Kwon Group has made major strides in the development and application of nucleophilic phosphinocatalysis reactions as a means to synthesize carbo- and heterocycles that serve as synthetic intermediates for both natural products and medicinally useful compounds.
Lambert Group – Professor Product Portal
Prof. Tristan Lambert and his co-coworkers have developed a new class of highly effective chiral Brønsted base catalysts, formulated from the unique cyclopropenimine architecture.
Li Group – Professor Product Portal
Research in Prof. Gang Li's lab includes transition-metal-catalyzed C–H bond activation reactions and small molecule activation.
Louie Group – Professor Product Portal
Professor Louie's research focuses on the discovery and mechanistic understanding of new reactions catalyzed by transition metal complexes. She has developed a highly active Ni(0) catalyst that effectively mediates a variety of cycloaddition and isomerization reactions.
Anita Mattson – Professor Product Portal
Boronate ureas benefit from internal Lewis acid coordination of the urea cabonyl oxygen and the strategically placed boron. As a result of this structural feature, boronate ureas can be rendered more acidic than conventional urea hydrogen bond donor catalysts.
Shi Group – Professor Product Portal
The major research interests of Prof. Bing-Feng Shi's lab are focused on transition metal-catalyzed transformations and their application in the synthesis of natural products.
Birman Group – Professor Product Portal
The main focus of research in the Birman group is on the de novo design of asymmetric catalysts and reagents. As part of this effort, they have developed Amidine-Based Catalysts, or ABCs, and demonstrated their high enantioselectivity in many asymmetric
Yamamoto Group – Professor Product Portal
The Yamamoto group has employed several applications in catalysis.
Vendrell Group – Professor Product Portal
Optical imaging has revolutionized our understanding of how biological systems behave at a molecular level. In our group we develop Dynamic Activatable Fluorophores (DYNAFLUORS) as chemical probes to image molecular events associated to inflammation and cancer.
Weaver Group – Professor Product Portal
Organofluorine chemistry is an essential part of drug discovery programs as well as agrochemical programs and even plays a major role in materials chemistry. Despite the undeniable importance of fluorinated organic molecules, our ability to synthesize these substrates is lacking
Trovitch Group – Professor Product Portal
The Trovitch laboratory is working to develop first-row transition metal catalysts that can be used to achieve a variety of organic transformations. The first complexes from this group made available through Sigma-Aldrich are the hydrosilylation catalysts, (Ph2PPrPDI)Mn and (Ph2PPrDI)Ni. Although
Wu Group – Professor Product Portal
The Wu Group works with Sigma-Aldrich in providing a portfolio of reagents and systems for carbonylation transformations.
Wilson Group – Professor Product Portal
The Wilson group use innovative synthetic methods to develop small molecule mimics and probes of biomacromolecule structure and function. A particular focus centers on the synthesis of non-natural amino acids (p-trifluoromethyldiazirine-phenylalanine and α-pentenyl-glycine).
Wulff Group – Professor Product Portal
The research areas of interest to the Wulff group include enantioselective catalysis, mechanisms of asymmetric catalysis, macromolecular chemistry, Fischer carbene complexes in organic synthesis and the total synthesis of natural products.
Strauss Group – Professor Product Portal
The Strauss group has been among the leaders in the synthesis and applications of new superweak anions for the past three decades.
Stahl Group – Professor Product Portal
he Stahl Lab focuses on the development of catalysts and catalytic reactions for selective oxidation of organic molecules, with particular emphasis on aerobic oxidation reactions.
Stephenson Group – Professor Product Portal
Research in the Stephenson lab focuses upon the development of new chemical methods which enable the activation of chemical bonds under mild reaction conditions.
Garg Group – Professor Product Portal
The Garg group develops methods for the synthesis of natural products and pharmaceuticals. One key method pertains to heterocyclic arynes, such as indolynes and pyridynes, which are generated in situ from silyltriflate precursors under mild fluoride based reaction conditions.
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