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11813

Sigma-Aldrich

Potassium cyanide

technical, ≥96%

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About This Item

Linear Formula:
KCN
CAS Number:
151-50-8
Molecular Weight:
65.12
Beilstein:
3593645
EC Number:
205-792-3
MDL number:
MFCD00011397
UNSPSC Code:
12352302
PubChem Substance ID:
329749561
NACRES:
SB.54

grade

technical

Assay

≥96%

form

solid

pH

11.5 (20 °C, 20 g/L)

mp

634 °C (lit.)

cation traces

Na: ≤5000 mg/kg

SMILES string

[K]C#N

InChI

1S/CN.K/c1-2;

InChI key

YUZRZFQHUCKACF-UHFFFAOYSA-N

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Application


  • Characterization, antimicrobial and antitumor activity of superoxide dismutase extracted from Egyptian honeybee venom (Apis mellifera lamarckii).: This study explores the extraction and characterization of superoxide dismutase from honeybee venom, highlighting its antimicrobial and antitumor properties. Potassium cyanide was used in the biochemical analysis to understand the enzyme′s activity and stability (Abdel-Monsef et al., 2023).

  • Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib.: This research investigates the metabolic pathways of masitinib, focusing on the role of cytochromes P450. Potassium cyanide is used to inhibit specific enzymatic activities during the analysis, providing insights into drug metabolism and potential toxicological impacts (Latham et al., 2022).

  • Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry.: The study details the metabolic profiling of zorifertinib using advanced chromatographic techniques. Potassium cyanide serves as an analytical reagent to assess the stability and reactivity of various metabolites (Al-Shakliah et al., 2022).

  • Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum.: The research characterizes a peroxidase enzyme from Dictyostelium discoideum, utilizing potassium cyanide in the enzymatic assays to inhibit specific reactions and better understand the enzyme′s functionality (Rai et al., 2021).

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

Target Organs

Thyroid

Supplementary Hazards

EUH032

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Eagleson M.
Concise Encyclopedia Chemistry, 887-887 (1994)
Reaction of the Methiodide of N, N-Dimethylaminomethylferrocene with Potassium Cyanide to Form Ferrocylacetonitrile1.
Lednicer D, et al.
The Journal of Organic Chemistry, 23(5), 653-655 (1958)
Catalytic asymmetric synthesis of O-acetylcyanohydrins from potassium cyanide, acetic anhydride, and aldehydes, promoted by chiral salen complexes of titanium (IV) and vanadium (V).
Belokon YN, et al.
Helvetica Chimica Acta, 85(10), 3301-3312 (2002)
Sónia C Correia et al.
Neurobiology of disease, 45(1), 206-218 (2011-08-23)
The current study was undertaken to address the role of mitochondrial reactive oxygen species (ROS), and hypoxia inducible factor-1 alpha (HIF-1α) signaling pathway in the protection against high glucose levels in brain endothelial and NT2 neuron-like cells. Rat brain endothelial
Vikhyat S Bebarta et al.
Annals of emergency medicine, 64(6), 612-619 (2014-04-22)
Hydroxocobalamin is a Food and Drug Administration-approved antidote for cyanide poisoning. Cobinamide is a potential antidote that contains 2 cyanide-binding sites. To our knowledge, no study has directly compared hydroxocobalamin with cobinamide in a severe, cyanide-toxic large-animal model. Our objective
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