TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
Synonyms:
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
Species:
Human TGFBR2 (7048), Mouse Tgfbr2 (21813), Rat Tgfbr2 (81810), Horse TGFBR2 (100033860), Zebrafish tgfbr2 (30739), chicken TGFBR2 (396399), domestic guinea pig Tgfbr2 (100718284), dog TGFBR2 (477039), domestic cat TGFBR2 (101091725), cow TGFBR2 (535376) ...More
UniProtKB ID:
Gene ID:
- Human(7048) Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(21813) transforming growth factor, beta receptor II
- Rat(81810) transforming growth factor, beta receptor II
- Horse(100033860) transforming growth factor, beta receptor II (70/80kDa)
- Zebrafish(30739) transforming growth factor, beta receptor II
- chicken(396399) transforming growth factor, beta receptor II (70/80kDa)
- domestic guinea pig(100718284) transforming growth factor, beta receptor II (70/80kDa)
- dog(477039) transforming growth factor, beta receptor II (70/80kDa)
- domestic cat(101091725) transforming growth factor, beta receptor II (70/80kDa)
- cow(535376) transforming growth factor, beta receptor II (70/80kDa)
- sheep(494191) transforming growth factor, beta receptor II (70/80kDa)
- naked mole-rat(101704397) transforming growth factor, beta receptor II (70/80kDa)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-TGFBR2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, rabbit
Application
western blot
Anti-TGFBR2 Antibody, clone 1N11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-TGFBR2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TGF beta Receptor II (TGFBR2) Antibody, clone 2M8Y2, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
TGFβR2 (190-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
Species
human
esiRNA
Product Number
Description
Species